Summary: Synapses exhibit multiple forms of short-term plasticities, which have been attributed to the heterogeneity of neurotransmitter release probability.However, the molecular mechanisms that underlie the differential release states remain to be fully elucidated.The Unc-13 proteins appear Restorers / Maintainers to have key roles in synaptic fu
Changes in bacterial physiology necessarily precede cell death in response to antibiotics.Herein we investigate the early disruption of Ca2+ homeostasis as a marker for antibiotic response.Using a Collections machine learning framework, we quantify the temporal information encoded in single-cell Ca2+ dynamics.We find Ca2+ dynamics distinguish kanam
An acute poisoning with nitrobenzene presenting as methaemoglobinaemia is an uncommon medical emergency.Here, we report the case of a 33-year-old male presenting with an alleged history of consumption of an unknown substance 24 h ago.On admission, he was unconscious (Glasgow Coma Scale score 3) and gasping.General Hand Cream physical examination re
Caenorhabditis elegans neurons under stress can produce giant vesicles, several microns in diameter, called exophers.Current models suggest that exophers are neuroprotective, providing a mechanism for stressed neurons to eject toxic protein aggregates and organelles.However, little is known of the fate of the exopher once it leaves the neuron.We fo
In dressage, the performance of transitions between gaits and halts is an integral part of riding sessions.The study aimed to evaluate girls tankini rein tension before, during and after the transitions between different gaits and the transitions into halts.The kinematic (inertial measurement units) data for the head and croup, and rein tension dat